Wednesday, November 5, 2025

An unforeseen danger in a sleep supplement

 

I've used a melatonin supplement as a sleep aid for over a year.  I take one tablet at night before going to bed, and have found it helps me sleep more regularly, with less waking up in the middle of the night.

Unfortunately, I may have to stop that.  A new report says melatonin can be a two-edged sword.


New research has linked long-term melatonin use with a significantly increased risk of heart failure, hospitalization and death.

An observational study from the American Heart Association (AHA) examined five years of health records of 130,828 adults with insomnia, half of whom used melatonin for at least one year. The other half did not take the supplement.

People who were prescribed other sleep medications or already had confirmed heart failure were excluded from the analysis.

The researchers found that long-term melatonin use in those with chronic insomnia was linked to a 90% increased chance of incident heart failure compared to non-users.

Additionally, participants who filled at least two melatonin prescriptions at least 90 days apart had an 82% higher risk of developing heart failure compared with those who did not use melatonin, according to the observational study.

A secondary analysis revealed that participants who took melatonin were nearly 3.5 times as likely to be hospitalized for heart failure and twice as likely to die.


There's more at the link.

What I found particularly depressing was that this study deliberately excluded people who "already had confirmed heart failure".  That would include me, after two heart attacks.  If melatonin increased cardiac risks to the extent reported in people with healthy hearts, what about folks like me with unhealthy ones?

I know a number of people who use melatonin as I do - some of them recommended it to me.  It does work as a sleep aid, in my experience.  However, no matter how effective it may be in the latter capacity, if it's going to add to the stress on my heart, I'm going to have to stop using it.

Have any readers had experiences that might bear out this report?  If so, please tell us about them in Comments.

Peter


9 comments:

Mega Maga Gal said...

California’s “Useful Idiots”
With Proposition 50, voters handed the keys of redistricting back to the very politicians the independent commission was created to restrain. The so-called “Election Rigging Response Act” was sold as a way to “fight back” against Republican gerrymandering in Texas, but make no mistake, this was no act of resistance. It was an act of surrender.

Once upon a time, California prided itself on being the antidote to partisan manipulation of what was created at that time, known as the the California Citizens Redistricting Commission, a rare, voter-approved firewall against any political map-rigging. It was transparent, balanced, and it was independent! And it was run by ordinary citizens not politicians who decided how district lines were drawn. It was made to “Leveling the playing field” with Texas. But since when does California, the self-proclaimed bastion of fairness, justify one bad act by pointing to another? That’s like saying, “Texas cheats, so now we get to cheat too.” How stupid is that!
Now, these Democrats control not just the legislature, but also the Governorship, and most local governments — they also control the map itself. Every district can be tailored to preserve their dominance, it will silent the opposition, and make “Elections” little more than just being plain Formalities.
So what do ya know? Well it now appears that the REAL beneficiary of Proposition 50 is not the the Democrat Politicians who will be running for the newly created seats, but our Good Ole Friend Gavin Newsom, who has made himself a new list of donors for HIS Presidential campaign and access to large out-of-state donors likely to now fund a National campaign
known as the “Gavin Newsom Presidential Fundraiser”
So. Let’s face it, when one party faces NO real challenge, then corruption festers. And accountability dies. The voices of independents and moderates vanish. Prop 50 is more than a political maneuver — it’s the moment California officially gave up on pluralism.

The tragedy? The “useful idiots” who voted for it think they were saving democracy. In truth, they buried it under the weight of partisan arrogance.

Anonymous said...

A somewhat different (less alarming) take here: https://www.nbcnews.com/health/health-news/taking-melatonin-reveal-heart-health-rcna241132

Carteach said...

Dead link

Peter said...

All the links work for me. Try again?

pyotr said...

From my reading, the issue isn't melatonin, but the insomnia which may be connected to undetected heart issues.

in other words, people with undetected heart disease can't sleep so they take melatonin. Yes there is a correlation, but so is the one between apartment rent and GPA.

Anonymous said...

I used to take melatonin a couple times a week, sometimes every night. For me, it didn’t always work - I’d still be tossing and turning.
Now I just put up with lack of sleep. I also cut out the nightly glass of wine with dinner. Alcohol can cause some people to have interrupted sleep patterns. mostly it seems to have helped me. Generally, pain or discomfort keeps me awake, so I just read a little when I can’t sleep.
Southern NH

Paul M said...

Try Z-Factor from Relief Factor (www.relieffactor.com)....not Melatonin based...and not a drug.

M said...

I had read somewhere that the amount in the usual pills is actually about 10x what's needed for an effect.
Assuming it affects you at all. It doesn't seem to change my sleep patterns, so I stopped using it.

Pat said...

Can you really trust any of these reports? Looks like they all have agendas, paid for by some pharma group, no such thing as true peer review everyone is on the take.